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Myalgic Encephalomyelitis, which includes CFS, is classified as a neurological disease in the World Health Organization’s International Classification of Diseases (ICD).
Symptoms of CFS include post-exertional malaise; unrefreshing sleep; widespread muscle and joint pain; sore throat; headaches of a type not previously experienced; cognitive difficulties; chronic, often severe, mental and physical exhaustion; and other characteristic symptoms in a previously healthy and active person. Persons with CFS may report additional symptoms including muscle weakness, increased sensitivity to light, sounds and smells, orthostatic intolerance, digestive disturbances, depression, and cardiac and respiratory problems.
Fatigue is a common symptom in many illnesses, but CFS is comparatively rare. Estimates of CFS prevalence vary widely, from 7 to 3,000 cases of CFS for every 100,000 adults, but national health organizations have estimated more than 1 million Americans and approximately a quarter of a million people in the UK have CFS. CFS occurs more often in women than men, and is less prevalent among children and adolescents. The quality of life is "particularly and uniquely disrupted" in CFS.
The Canadian Consensus Document on ME/CFS.
“Myalgic Encephalomyelitis” and “Chronic Fatigue Syndrome” are used interchangeably and this illness is referred to as “ME/CFS”. The Expert Consensus Panel, selected by Health Canada, established clinical criteria, and developed an integrative diagnostic and treatment approach to ME/CFS.
Many infectious agents may trigger ME/CFS.
Antibiotic treatment for mycoplasma and chlamydia: Suggested antibiotic treatments for confirmed mycoplasma or chlamydia infections.
The majority of CFS cases start suddenly, usually accompanied by a "flu-like illness" while a significant proportion of cases begin within several months of severe adverse stress.
Most patients enjoyed a healthy, active lifestyle prior to the onset of ME/CFS.
In a review study of prognosisof studies indicated that 0% to 12% of adults return to their pre-illness level of functioning. Relapses can occur several years after remission. The prognosis for children and youth is much better.