エムバイオテック


			Respiratory Disorder

			Asthma Asthma and Mycoplasma pneumoniae infection
			Asthma is the common chronic inflammatory disease of the airways characterized by variable and recurring symptoms, reversible airflow obstruction, and bronchospasm. Symptoms include wheezing, coughing, chest tightness, and shortness of breath. Asthma is caused by environmental and genetic factors. These factors influence how severe asthma is and how well it responds to medication. Asthma may also be classified as atopic (extrinsic) or non-atopic (intrinsic). Although asthma is a chronic obstructive condition, it is not considered as a part of chronic obstructive pulmonary disease as this term refers specifically to combinations of disease that are irreversible such as bronchiectasis, chronic bronchitis, and emphysema. Unlike these diseases, the airway obstruction in asthma is usually reversible. The strongest risk factor for developing asthma is a history of atopic disease. The term "atopy" was coined to describe this triad of atopic eczema, allergic rhinitis and asthma. Asthma attack An acute asthma exacerbation is commonly referred to as an asthma attack. The classic symptoms are shortness of breath, wheezing, and chest tightness. Exacerbation of asthma Some individuals will have stable asthma for weeks or months and then suddenly develop an episode of acute asthma. Different asthmatic individuals react differently to various factors. However, most individuals can develop severe exacerbation of asthma from several triggering agents. Home factors that can lead to exacerbation include dust, house mites, animal dander (especially cat and dog hair), cockroach allergens and molds at any given home. Perfumes are a common cause of acute attacks in females and children. Both virus and bacterial infections of the upper respiratory tract infection can worsen asthma. Respiratory infections such as Mycoplasma pneumniae, Chlamydia pneumoniae and Bordetella pertussis are correlated with asthma exacerbations. C.D. 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Chiang, The significance of a rapid cold hemagglutination test for detecting mycoplasma infections in children with asthma exacerbation, J Microbiol Immunol Infect 39 (2006) 28-32. F. Freymuth, A. Vabret, J. Brouard, F. Toutain, R. Verdon, J. Petitjean, S. Gouarin, J.F. Duhamel, B. Guillois, Detection of viral, Chlamydia pneumoniae and Mycoplasma pneumoniae infections in exacerbations of asthma in children, J Clin Virol 13 (1999) 131-139.
			COPD COPD and Mycoplasma Infectious Diseases